Talk:Terbinafine

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Terbinafine.

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Renaming

In accordance with Wikipedia:WikiProject_Drugs naming policy, I propose we move this page to the INN terbinafine. If you have any concern with this proposal, please discuss it on this page. Matt 18:09, 23 Dec 2004 (UTC)

Fractions

Uhm...the last sentence is bogus - "a fraction of its former cost" ? That sounds super biased...I mean - if the drug cost a 100 bucks and the price dropped to 99. That's still a fraction of the former cost - that fraction is 99/100, but it is a fraction no less... —Preceding unsigned comment added by 24.107.191.175 (talk) 06:04, 6 September 2007 (UTC)[reply]

Is this drug really that expensive? You can get it over the counter for about ten dollars... Eugene Kwan (talk) 22:21, 16 July 2008 (UTC)[reply]

Lamisil $500 or $259 or $9

Lamisil $500 or $259 or $9 These are the prices quoted me today as I hunted for some sanity. Bottom line you can get a generic Lamisil for $9.00 for 30 pills at Walmart. You do the math on the mark ups at Rite Aid etc... —Preceding unsigned comment added by 76.229.125.123 (talk) 04:28, 25 July 2008 (UTC)[reply]

Here in Boston you can get Terbinafine for $4.00 for 30 pills at Wal-Mart. At any other drug store to get Lamisil brand is $450+ —Preceding unsigned comment added by 71.243.116.167 (talk) 13:18, 1 August 2008 (UTC)[reply]

As of 2015 in the US, the 1% topical cream is generic OTC for about $15/oz. But the 250mg oral tablets require a prescription and retail for well over $1 per tablet -- yet are commonly covered by various discount programs that can bring the cost down to about $10 per month (30 tablets). Insurance coverage is limited because nail problems may be classified as "cosmetic" and not included.-71.174.175.150 (talk) 16:24, 24 January 2015 (UTC)[reply]

Possible error in "Indications" section

It says "The antifungal granules can be sprinkled on a child's food to treat ringworm of the scalp, Tinea capitis". Really? Tinea capitis means fungal infection of the scalp, but will sprinkling the antifungal granules on a child's foot really treat a scalp problem?— Preceding unsigned comment added by 69.216.120.158 (talk) 23:39, 12 October 2008 (UTC)[reply]

yes because lamisil is a drug that bioaccumulates in fat when administered orally. I thought it was kind of peculiar too though. —Preceding unsigned comment added by 174.20.7.149 (talk) 04:55, 20 November 2009 (UTC)[reply]

fooD not fooT! 81.157.43.216 (talk) 07:54, 9 November 2014 (UTC)[reply]

Alcohol and terbinafine

"Alcohol consumption should also be avoided while taking terbinafine" - why not just state "Alcohol consumption should always be avoided" and re-introduce prohibition! More seriously, in the drug notes associated with Lamisil there is ZERO mention of alcohol affecting the drugs risk/effectiveness. —Preceding unsigned comment added by 203.198.252.42 (talk) 06:49, 9 January 2008 (UTC)[reply]

The presumable rationale for alcohol avoidance would be that both drugs are metabolized by the liver, a detail which strongly suggests that there is an increased risk of synergistic hepatotoxic effects in some populations. — C M B J 09:44, 8 June 2010 (UTC)[reply]

Link to liver enzymes

The separate links to liver and enzymes separately wouuld (especially for the layman) be more useful as a single link to liver enzymes, it seems to me (as a layman). 198.184.231.254 (talk) 14:26, 13 May 2011 (UTC) (PJTraill not logged in)[reply]

outward appearance of oral terbinafine

i have been prescribed terbinafine for fungus in my toenails but the bottle says the pill should say one thing but the pill says something different than the description on the bottle. the pill is imprinted with IG on one side and 209 on the other side. and the bottle says it should say 250 on one side and RDY on the other side. does anyone know what this means? — Preceding unsigned comment added by 71.198.110.121 (talk) 03:58, 29 October 2011 (UTC)[reply]

I just filled a prescription for terbinafine, and the bottle and pills match: both IG/209. So I think you have the right stuff. ACW (talk) 00:13, 24 December 2011 (UTC)[reply]

Pill images: * www.drugs.com/terbinafine-images.html -71.174.175.150 (talk) 16:16, 24 January 2015 (UTC)[reply]

Unlisted Side Effect

I am around 6 weeks into a course of Terbinafine tablets...just thought it worth mentioning a side effect that is not listed here. Within the first 2 days of taking it, I felt a "tightening" in my left hand...within another couple of days it almost felt like I was wearing a tight rubber glove...and after around 7-10 days I started apparently shedding a layer of skin! But only from my left hand. All was fine after about another week.

I know I can't add this to the article, but thought it worth mentioning here in case a Doctor or expert on the medication recognises this, can match it in with something else and perhaps add it later.195.92.40.49 (talk) 06:53, 5 March 2012 (UTC)[reply]

When was terbinafine discovered, and how named?

I wondered when terbinafine was discovered, and what the name meant, since it doesn't seem to describe a chemical formula. The article states when the patent expired, making it generic, but not when it was discovered, or first released. There is nothing about the name, either. Perhaps someone could add this info?Anonnymos (talk) 09:15, 20 August 2013 (UTC)[reply]

Clarification under Side Effects

After the first sentence under the Side Effects heading, after the references it states that clarification is needed as to whether the effects mentioned apply to topical or oral use. I am here to offer my view that it is mostly referring to oral use. I use terbinafine topically regularly & experience no side effects whatsoever, but a recent visit to my podiatrist has led me to believe that its oral use has some pretty serious side effects. I can say with certainty that at the very least, the hepatic & gastrointestinal side effects can only be achieved with oral use, because otherwise the drug does not enter the liver nor the digestive tract. I find it unlikely that the neurological & sensory effects can result from topical use either. However, the skin effects are almost certainly due to topical use.

Perhaps we should separate the side effects into oral & topical, but it would help if we could find some references to clarify this issue. I'll get to work on that right now & post here again if I find any.

(Psychonaut25 - 13375p34k / C0n7r1b5 08:59 PM EST, 26 March 2014 (UTC))

Moved from article

I have moved the following content here because it lacks context/explanation. If anyone wants to use it to improve the article, here it is. -- Ed (Edgar181) 18:47, 6 October 2015 (UTC)[reply]

[[File:Terbinafinesynthesis.svg|thumb|center|1000px|Terbinafine synthesis:<ref>A. Stütz, {{Cite patent|EP|24587}}; idem, {{US patent|4755534}} (1981, 1988 both to [[Sandoz]]).</ref><ref>{{Cite journal |title=Synthesis and antifungal activity of (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine (SF 86-327) and related allylamine derivatives with enhanced oral activity |author1=Stuetz, Anton |author2=Petranyi, Gabor |journal=Journal of Medicinal Chemistry |volume=27 |issue=12 |pages=1539-1543 |date=December 1984 |doi=10.1021/jm00378a003}}</ref>]]

Hearing impairment

There is a serious side effect missing from the article. Hearing impairment was investigated by Scholl and van Puijenbroek. This is an original research article, so I'm certain someone will object if I insert this directly in the article's side effects section. In any case, the publication is the following if anyone is interested: "Hearing Impairment Associated with Oral Terbinafine Use. A Case Series and Case/Non-Case Analysis in the Netherlands" (2012). Pharmacovigilance Centre Lareb Database and VigiBase�. Authors: Joep H.G. Scholl and Eugene P. van Puijenbroek. Netherlands Pharmacovigilance Centre Lareb, ‘s-Hertogenbosch, the Netherlands. — Preceding unsigned comment added by 131.211.210.235 (talk) 16:28, 28 February 2016 (UTC)[reply]

No side effects section for spray and topical solution formulations

Currently there is only a section describing the oral formulation side effects, but no mention of the side offects for the spray and topical solution of terbinafine. — Preceding unsigned comment added by 131.211.210.235 (talk) 16:30, 28 February 2016 (UTC)[reply]

Terbinafine hydrochloride vs Terbinafine

Lamisil has what look two identical products in my part of the world. One product states it contains terbinafine hydrochloride and the other justs states terbinafine. This article mentions both. If they are the same chemical compound, can this please be made clear in the article. Thanks. — Preceding unsigned comment added by 60.224.216.202 (talk) 07:18, 1 May 2018 (UTC)[reply]

Added Side Effect

The depression side effect is greatly understated. It causes great personality changes. It will make you have no interest in the people or things you cared deeply for before. It literally snatches your soul. It causes suicidal thoughts, self loathing, and caused my friend to end relationships and withdraw from life. It will cause you to walk through life with no joy. My friend is going on two months off this medicine, and he still does not act, talk, or smile as he once did. Save yourself lots of heartache and those you love by not taking this. Your mental health is worth more than pretty nails.

Concerngf1234 (talk) 04:44, 26 January 2022 (UTC)concerned friend[reply]