Talk:Teratoma

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Fact check

Inserted by an anonymous user:

The stem cells which are produced by teratocarcinoma were used for medicinal purposes, but only in a few experiments. Per example, a teratoma producing nerval tissue helped restore the brain of a man suffering a stroke.

Does anyone have a reference to substantiate this? It sounds a bit tall to me; stem cells are being considered for Parkinson's, but AFAIK not for CVAs. JFW | T@lk 10:25, 10 Oct 2004 (UTC)

Pluripotent -> Totipotent

According to Robbins Pathologic Basis of Disease, teratomas arise from totipotent cells. Anyone any arguments for the 'pluripotent' as stated here in the first line?

I have not seen the term "pluripotent" in the medical literature on teratomas that I have read. The usual term is "totipotent". However, per Google the terms "pluripotent" and "totipotent" occur at a ratio of 5:1. And they mean essentially the same thing. 66.167.45.138 04:02, 26 January 2007 (UTC)[reply]

Pluripotent and totipotent are not the same thing. Totipotent cells can form trophectoderms while pluripotent cells can't

Fair enough. In the context of this page, though, the question is: does teratoma derive from one or the other cell type, or both? Una Smith 14:36, 8 April 2007 (UTC)[reply]

(N.B. I have knowledge of TSCs and PSCs, but not of teratoma specifically.) Totipotent cells can produce any type of cell (total potential), pluriporent cells can produce many types of related cell (plural potential). Pluripotent cells are derived from totipotent cells. Since the cause of a teratoma is a cell becoming cancerous before going along any one line, it would make sense than a cancer of either of these types of cell would cause something along the lines of a teratoma. Although totipotent cells could provide a lot more variety and therefore are more interesting, they are not really found after the first few weeks of gestation, so if they mutate, are less likely to be compatible with life as a foetus is very sensitive to that sort of thing. I expect mutations of pluripotent cells are far more common as there are more of them and they last throughout life, but less interesting; but I don't know if they would have a different name.--KX36 (talk) 14:45, 20 November 2008 (UTC)[reply]

I think the article needs some refs re this question of origin, and explanation. (Refs first!) Medical case reports and other articles about teratomas often begin by repeating the "totipotent" story, but what is the basis for that story? --Una Smith (talk) 21:07, 3 December 2008 (UTC)[reply]

Incidence of teratomas by location

I removed the following list item because it hints at a larger table, but has only one entry from the bottom of that table, which just looks a bit odd sitting by itself out there. It's kind of like saying, "1% of teratomas are gastric", which is sort of trivia without information about that other 99%. Really the solution is to have a complete table of teratoma incidence by location, but until that becomes available, I've moved the graf here.Collabi 19:42, 28 April 2007 (UTC)[reply]

Stomach 1%^[1]

References

^ Immature gastric teratoma of the lesser curvature in a male infant, Utsch et al (2001) Journal of Pediatric Gastroenterology and Nutrition 32:204-206

External link

Why is http://health.groups.yahoo.com/group/teratomas/ being removed? Fred Bauder 01:26, 10 September 2007 (UTC)[reply]

Because it is without question external link spam. Someone else removed a link to another support group. I allowed that one because that group has a public archive. This one does not, so I do not know that it is in fact what its promoters purport it to be. I am not the only editor who has removed it, BTW. Are you a subscriber? If not, what is your interest? --Una Smith 16:15, 10 September 2007 (UTC)[reply]

Una,

How is it that you have decided unilaterally to classify this link as spam?

Baby with a large facial teratoma cured by surgery (with photos)

It is without question not spam, it is the story of a little girl from California who suffered a large facial teratoma and was cured by surgery. It contains photos of the teratoma and may be of interest to Wikipedia readers who are interested in learning more about teratomas. There are no ads or references to objectionable material in the article or anywhere on the site, perhaps you deleted it in error.

I believe if you refer to Wikipedia's policy on external links, you will see that the story about the little girl with the teratoma fits the criteria of being an appropriate link.

Lastly, after reading this, I hope you are acting sincerely and netutrally regarding this issue. Above you mention that you allowed a link to another support group because it has a public archive, but from this, it appears as if it was you who added the link.

I am hoping that this is a misunderstanding and that your POV is neutral and within the spirit of Wikipedia.

60.51.252.34 23:54, 17 September 2007 (UTC)[reply]

History

Misc. snippets for future history section. --Una Smith (talk) 22:55, 14 January 2008 (UTC)[reply]

Old terms for teratoma: dysembryoma.

picture suggestion

not sure how to add pictures, but i think this one would be good [1] —Preceding unsigned comment added by Mongreilf (talk • contribs) 16:05, 19 May 2008 (UTC)[reply]

Considering the frankly disturbing nature of pictures of this disorder, I would argue they should be linked to and not added to the page. 69.248.158.72 (talk) 22:55, 9 November 2008 (UTC)[reply]

umm hey dude i would argue you should get over yourself and remember that wikipedia is not censored 172.130.54.176 (talk) 04:31, 10 December 2008 (UTC)[reply]

Um, was that picture even originally a teratoma? I seriously have my doubts. It looks like just an artistic photshop job to me. — NRen2k5^(TALK), 19:22, 17 December 2008 (UTC)[reply]

Which picture? File:Mature cystic teratoma of ovary.jpg (used in the article now) is by a pathologist whose website has many equally informative photos. Also, I have seen similar photos in pathology textbooks and elsewhere. --Una Smith (talk) 22:15, 17 December 2008 (UTC)[reply]

I think an interesting, non-disgusting photograph could be found without a great deal of difficulty. For example, for several months, one of our dogs had a teratoma -- a toenail growing in the middle of her ear. It looked odd but not disgusting. It eventually just fell off. The doctor said they were quite common in dogs. 71.175.4.207 (talk) 15:14, 23 September 2010 (UTC)[reply]

New section: Teratomas in popular culture?

Is it appropriate to add a section "Teratomas in popular culture"? Stephen King's The Dark Half, Grey's Anatomy: Something to Talk About (Grey's Anatomy)...? samwaltz (talk) 22:38, 23 April 2010 (UTC)[reply]

Good idea - Louis de Berniere's "The Troublesome Offspring of Cardinal Guzman" includes a significant passage involving the discovery of an unusually developed Teratoma. Butcherscross (talk) 15:16, 5 August 2010 (UTC)[reply]

Possible Reference Article

Doctors induce 5-month coma to save woman's life It seems this poor woman had a rare reaction to a teratoma - antibodies produced in response to a teratoma started attacking her healthy brain. Thought it might be of some interest here Jedikaiti (talk) 22:54, 3 November 2010 (UTC)[reply]

I have a question: how do fully formed limbs, hands, feet, and organs form like this? fetiform teratomas have been knonw tho have entire heads, how do these devolp? has it eveyr been thought to ariffically induce them for organ harvesting? 173.160.74.137 (talk) 08:08, 4 April 2011 (UTC)[reply]

"Fetus" in Teratoma

Does anyone have more information on this? It's far outside of my expertise, but as a reader I am fascinated by this and think it could (maybe?) be expanded on in the article by someone more knowledgeable. 174.17.180.214 (talk) 10:49, 6 September 2011 (UTC)[reply]

Why does "dysembryoma" redirect here?

The word is not used or explained in the article. 86.159.197.174 (talk) 05:40, 13 August 2014 (UTC)[reply]

It is a term often used synonymously with teratoma. I will add some coverage of synonyms/hypernyms/hyponyms in the article. Quercus solaris (talk) 17:08, 13 August 2014 (UTC)[reply]

Thanks. 86.159.197.174 (talk) 09:04, 15 August 2014 (UTC)[reply]

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Paragraph 2, Sentence 5

Did anyone else find this unnecessarily sexist?70.66.132.146 (talk) 06:31, 7 March 2018 (UTC)[reply]

[1] Immature gastric teratoma of the lesser curvature in a male infant, Utsch et al (2001) Journal of Pediatric Gastroenterology and Nutrition 32:204-206

[1]